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KMID : 1140120080130040297
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Cancer Prevention Research
2008 Volume.13 No. 4 p.297 ~ p.301
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Serum Selenium Level in Healthy Koreansby GF-AAS and ICP-MS
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Abstract
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In the present study, the serum selenium level was determined in 100 healthy Koreans of both genders using Graphite Furnace Atomic Absorption Spectrometry (GF-AAS) and Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The experimental results showed that the mean serum selenium level in healthy Koreans was 105.58±24.06μg/l, and it was 102.82±22.21μg/l among males and 108.34±25.71μg/l (p=0.25) among women by the GF-AAS (Limit of detection (LOD) was 1.12μg/l) method, while the mean was 112.05±30.42μg/l for the whole studied subjects, and 103.29±31.05μg/l for men and 120.81±27.37μg/l (p=0.0035) for women in the case of ICP-MS (LOD=0.01μg/l), respectively. To sum up, the data from the study suggested that the healthy Koreans have a quite moderate-selenium level in their blood serum when compared with the values reported in other countries. However, Se level in serum should be improved with the help of Se-rich food products for the population to prevent from the serious chronic diseases, particularly cancer.
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KEYWORD
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Selenium, Serum, Graphite furnace atomic absorption and inductively coupled plasma mass spectrometry
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